Tuftsin diacetate
CAS No. 72103-53-8
Tuftsin diacetate ( —— )
产品货号. M30544 CAS No. 72103-53-8
Tuftsin diacetate, a tetrapeptide, is a macrophage/microglial activator. Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥5702 | 有现货 |
|
10MG | ¥9720 | 有现货 |
|
25MG | ¥19764 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
5MG | ¥5702 | 有现货 |
|
10MG | ¥9720 | 有现货 |
|
25MG | ¥19764 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称Tuftsin diacetate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Tuftsin diacetate, a tetrapeptide, is a macrophage/microglial activator. Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages.
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产品描述Tuftsin diacetate, a tetrapeptide, is a macrophage/microglial activator. Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages.(In Vitro):Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animal model for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors.
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同义词——
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通路Proteasome/Ubiquitin
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靶点Endogenous Metabolite
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number72103-53-8
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分子量620.7
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分子式C25H48N8O10
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:Thr-Lys-Pro-Arg
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Fridkin M, et al. Tuftsin: its chemistry, biology, and clinical potential. Crit Rev Biochem Mol Biol. 1989;24(1):1-40.
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